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<blockquote data-quote="pavlosn" data-source="post: 686817" data-attributes="member: 22572"><p>I have taken Metformin since diagnosis in 2009 and continue to do so despite a non-diabetic latest hba1c of 5,2% (33 mmol) ; I am of course still diabetic.</p><p></p><p>I choose to do so as I consider that my current combination of medication/diet/exercise works for me so why fix something if it's not broken.</p><p>I am also aware that Metformin has beneficial effects that extend beyond glycemic control, as [USER=97664]@jack412[/USER] mentioned.</p><p></p><p>This is my personal choice though and I fully understand why others such as yourself may wish to go down the diet and exercise only route.</p><p></p><p>Even with metformin, diet and exercise, are still the primary means of reducing glucose levels; metformin's estimated impact on Hba1c is estimated at about 1% reduction in score when expressed in the old percentage terms.</p><p></p><p>Metformin does not cause insulin secretion by the pancreas it has a twofold action, it reduces insulin resistance of our body cells and also reduces glucose production by the liver. </p><p></p><p>I suspect that the impact on the liver reduces dawn phenomenon; the frustrating tendency for blood sugar levels to rise before dawn, irrespective of diet, as our liver releases glycogen which then turns to glucose elevating our blood sugar levels in anticipation of the coming day's energy demands.</p><p></p><p>Pavlos</p></blockquote><p></p>
[QUOTE="pavlosn, post: 686817, member: 22572"] I have taken Metformin since diagnosis in 2009 and continue to do so despite a non-diabetic latest hba1c of 5,2% (33 mmol) ; I am of course still diabetic. I choose to do so as I consider that my current combination of medication/diet/exercise works for me so why fix something if it's not broken. I am also aware that Metformin has beneficial effects that extend beyond glycemic control, as [USER=97664]@jack412[/USER] mentioned. This is my personal choice though and I fully understand why others such as yourself may wish to go down the diet and exercise only route. Even with metformin, diet and exercise, are still the primary means of reducing glucose levels; metformin's estimated impact on Hba1c is estimated at about 1% reduction in score when expressed in the old percentage terms. Metformin does not cause insulin secretion by the pancreas it has a twofold action, it reduces insulin resistance of our body cells and also reduces glucose production by the liver. I suspect that the impact on the liver reduces dawn phenomenon; the frustrating tendency for blood sugar levels to rise before dawn, irrespective of diet, as our liver releases glycogen which then turns to glucose elevating our blood sugar levels in anticipation of the coming day's energy demands. Pavlos [/QUOTE]
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