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So what really causes type II?
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<blockquote data-quote="phoenix" data-source="post: 740689" data-attributes="member: 12578"><p>What causes T2?</p><p>Lots of things!</p><p>One senior UK researcher, prof Edwin Gale said last year said it was a category error, a diagnosis of exclusion.</p><p>' In practice, when somebody like myself talks about type 2 diabetes, I'm saying 'a form of diabetes for which I can find no other cause.'</p><p>'it is a "ragbag" of conditions "................."all wrapped up into one definition -- which is fair enough, except that people forget it."</p><p>'multifactorial diseases can't be defined in terms of their cause'</p><p>He says it should be called idiopathic hyperglycaemia (raised glucose for unknown reasons so people don't fall into the trap of thinking it's one condition .(with one treatment pathway)</p><p>The original paper is no longer free access but you can see a video with Professor Gale explaining his position.</p><p>[MEDIA=youtube]CxUiM5684Kg[/MEDIA]</p><p></p><p>Re Steve Redgrave</p><p></p><p></p><p><a href="http://www.clinmed.rcpjournal.org/content/3/4/333.long" target="_blank">http://www.clinmed.rcpjournal.org/content/3/4/333.long</a></p><p>so diagnosed with T2 However he also had a history of steroid induced diabetes and only ICA antibodies were tested (Glutamic acid decarboxylase autoantibodies (GADA), islet cell autoantibodies (ICA), insulinoma-associated (IA-2) autoantibodies, and zinc transporter autoantibodies (ZnT8) can all be associated with LADA)</p><p>( 1997 is a long time ago in LADA terms, most people are now tested for anti GAD and I don't think that Zn T8 antibodies had even been discovered! )</p></blockquote><p></p>
[QUOTE="phoenix, post: 740689, member: 12578"] What causes T2? Lots of things! One senior UK researcher, prof Edwin Gale said last year said it was a category error, a diagnosis of exclusion. ' In practice, when somebody like myself talks about type 2 diabetes, I'm saying 'a form of diabetes for which I can find no other cause.' 'it is a "ragbag" of conditions "................."all wrapped up into one definition -- which is fair enough, except that people forget it." 'multifactorial diseases can't be defined in terms of their cause' He says it should be called idiopathic hyperglycaemia (raised glucose for unknown reasons so people don't fall into the trap of thinking it's one condition .(with one treatment pathway) The original paper is no longer free access but you can see a video with Professor Gale explaining his position. [MEDIA=youtube]CxUiM5684Kg[/MEDIA] Re Steve Redgrave [url]http://www.clinmed.rcpjournal.org/content/3/4/333.long[/url] so diagnosed with T2 However he also had a history of steroid induced diabetes and only ICA antibodies were tested (Glutamic acid decarboxylase autoantibodies (GADA), islet cell autoantibodies (ICA), insulinoma-associated (IA-2) autoantibodies, and zinc transporter autoantibodies (ZnT8) can all be associated with LADA) ( 1997 is a long time ago in LADA terms, most people are now tested for anti GAD and I don't think that Zn T8 antibodies had even been discovered! ) [/QUOTE]
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