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Type 2 Diabetes
Strong genetic disposition to type 2: diabetes inevitable?
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<blockquote data-quote="kesun" data-source="post: 1170413" data-attributes="member: 39776"><p>Deff Jeff, have you been tested for any of the monogenic or mitochondrial types of diabetes (also known as MODY)? My consultant thinks that all non-obese people with a T2 diagnosis should be tested, but most doctors just classify all diabetes that isn't T1 as T2. The importance of getting tested is that treatment can vary a lot depending on the type, and metformin (first resort for T2) is useless for most MODYs.</p><p></p><p>My diabetes is mitochondrial (i.e. anyone can have it but only your mother can pass it on!), but I think most monogenic types are autosomal. In my case, both my mother and my grandmother are slightly overweight; grandmother didn't develop DB till her 90s, mother shows no sign in her 70s, I developed it in my 30s, my brother in his 40s. Well-fed Gen X! I've never been overweight, but I can now see I was over-loading a weak insulin production with too many "healthy" carbs - you know, wholemeal bread with low-fat spread type thing.</p><p></p><p>Kate</p></blockquote><p></p>
[QUOTE="kesun, post: 1170413, member: 39776"] Deff Jeff, have you been tested for any of the monogenic or mitochondrial types of diabetes (also known as MODY)? My consultant thinks that all non-obese people with a T2 diagnosis should be tested, but most doctors just classify all diabetes that isn't T1 as T2. The importance of getting tested is that treatment can vary a lot depending on the type, and metformin (first resort for T2) is useless for most MODYs. My diabetes is mitochondrial (i.e. anyone can have it but only your mother can pass it on!), but I think most monogenic types are autosomal. In my case, both my mother and my grandmother are slightly overweight; grandmother didn't develop DB till her 90s, mother shows no sign in her 70s, I developed it in my 30s, my brother in his 40s. Well-fed Gen X! I've never been overweight, but I can now see I was over-loading a weak insulin production with too many "healthy" carbs - you know, wholemeal bread with low-fat spread type thing. Kate [/QUOTE]
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Strong genetic disposition to type 2: diabetes inevitable?
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