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Type 2 Diabetes
T2 or NAFLD? ...or, a funny thing happened on the way to the surgery
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<blockquote data-quote="Chris24Main" data-source="post: 2697451" data-attributes="member: 585131"><p>Much the same for the third.</p><p></p><p>Inflammation - to go back to my net analogy, is damage to cell wall lining, in the form of breakage to the carbon strings that are the fatty acid chains. At the arterial level (where it's most pertinent to heart disease and plaque formation) its better to think of the endothelial cells as nice, shiny flat tiles on your kitchen floor. They are amazingly complex and they line all of your arteries, and are better thought of as a complete organ - they control all of the transport of molecules from the blood and can communicate with other organs, mainly the liver - I don't pretend to understand even a tiny portion of how it works..</p><p></p><p>But - inflammation causes these cells to curl up and holler for help from the inflammation response, which piles in to do repair, but also the curling up creates gaps between the cells where nasties can now get stuck, and need to get covered over with a whole bunch of stuff (clotting cascade, which is tremendously complex) finally being capped off with our old friend LDL and Cholesterol..</p><p></p><p>So - there is a connection between insulin resistance and inflammation - yes, of course there is... it's all about the sugar..</p></blockquote><p></p>
[QUOTE="Chris24Main, post: 2697451, member: 585131"] Much the same for the third. Inflammation - to go back to my net analogy, is damage to cell wall lining, in the form of breakage to the carbon strings that are the fatty acid chains. At the arterial level (where it's most pertinent to heart disease and plaque formation) its better to think of the endothelial cells as nice, shiny flat tiles on your kitchen floor. They are amazingly complex and they line all of your arteries, and are better thought of as a complete organ - they control all of the transport of molecules from the blood and can communicate with other organs, mainly the liver - I don't pretend to understand even a tiny portion of how it works.. But - inflammation causes these cells to curl up and holler for help from the inflammation response, which piles in to do repair, but also the curling up creates gaps between the cells where nasties can now get stuck, and need to get covered over with a whole bunch of stuff (clotting cascade, which is tremendously complex) finally being capped off with our old friend LDL and Cholesterol.. So - there is a connection between insulin resistance and inflammation - yes, of course there is... it's all about the sugar.. [/QUOTE]
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