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Type 1 Diabetes
Trial of therapy to restore insulin production in Type 1's
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<blockquote data-quote="tim2000s" data-source="post: 998839" data-attributes="member: 30007"><p>Anyhow, I've now read the research paper. And what the press has reported is not strictly what the study achieved or showed. The aim was to prove that extraction, expansion and reinfusion of Regulatory T-Cells with certain characteristics could be safely undertaken. This study proved it could and opens up options for future research.</p><p></p><p>The study was a phase 1 trial with n=14, which is far too low a number to draw any conclusions from. The metabolic responses of the majority of participants showed a decline in C-peptide levels in line with what is normally observed with the onset of diabetes, and they were unable to determine whether the T-reg infusion would prevent the progression of the autoimmune condition.</p><p></p><p>I've written a blog post summarising it, but suffice to say it is really bad reporting from all the newspapers involved.</p></blockquote><p></p>
[QUOTE="tim2000s, post: 998839, member: 30007"] Anyhow, I've now read the research paper. And what the press has reported is not strictly what the study achieved or showed. The aim was to prove that extraction, expansion and reinfusion of Regulatory T-Cells with certain characteristics could be safely undertaken. This study proved it could and opens up options for future research. The study was a phase 1 trial with n=14, which is far too low a number to draw any conclusions from. The metabolic responses of the majority of participants showed a decline in C-peptide levels in line with what is normally observed with the onset of diabetes, and they were unable to determine whether the T-reg infusion would prevent the progression of the autoimmune condition. I've written a blog post summarising it, but suffice to say it is really bad reporting from all the newspapers involved. [/QUOTE]
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Trial of therapy to restore insulin production in Type 1's
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