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Diabetes Discussion
Type 1 Diabetes
why do some people get the choice of a pump?
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<blockquote data-quote="tim2000s" data-source="post: 937058" data-attributes="member: 30007"><p>It's important to remember that dose size makes a very large difference to the action of Levemir. As the clamp graph shows, at doses below 0.2u/kg of body weight, whilst there is a peak, it's incredibly soft and the duration of the action is about eight hours with a long tail where it does very little for the next eight hours. What this means in practice is that it kicks in after about an hour, and I find that it doesn't really have a "sudden" effect. Once you get up to larger doses, the peakiness increases and gets pushed out to about eight hours. </p><p></p><p><img src="http://api.ning.com/files/7C-F8e0yGIYcL9eM6J8s308ECv4v-Ot*C0fw0QuEtmfdp94gF-6ReBK66Gj9AQT6V6tcskqqFEauMyix8q4zBF4U7Ury0NkR/Levimirspeeddose.jpg" alt="" class="fr-fic fr-dii fr-draggable " style="" /></p><p></p><p>This is why splitting the Levemir dose is a good idea. It reduces the impact of that peak.</p></blockquote><p></p>
[QUOTE="tim2000s, post: 937058, member: 30007"] It's important to remember that dose size makes a very large difference to the action of Levemir. As the clamp graph shows, at doses below 0.2u/kg of body weight, whilst there is a peak, it's incredibly soft and the duration of the action is about eight hours with a long tail where it does very little for the next eight hours. What this means in practice is that it kicks in after about an hour, and I find that it doesn't really have a "sudden" effect. Once you get up to larger doses, the peakiness increases and gets pushed out to about eight hours. [IMG]http://api.ning.com/files/7C-F8e0yGIYcL9eM6J8s308ECv4v-Ot*C0fw0QuEtmfdp94gF-6ReBK66Gj9AQT6V6tcskqqFEauMyix8q4zBF4U7Ury0NkR/Levimirspeeddose.jpg[/IMG] This is why splitting the Levemir dose is a good idea. It reduces the impact of that peak. [/QUOTE]
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why do some people get the choice of a pump?
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