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A Puzzling Question I Have Not Yet To Find An Answer

HICHAM_T2

Well-Known Member
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1,447
Location
Morocco
Type of diabetes
Type 2
Treatment type
Diet only
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Hi


In fact, I have already asked this question before and I have no answer. I hope not to be bothered by the repetition of the question

Many members know that diabetes T2 is caused by cell resistance to insulin
Sometimes insulin production is many

My Question Is :
Why cells accept external insulin while not accepting internal natural insulin ?

Is there a difference between them in amino acids ?
 
Last edited:

If a person is injecting external insulin, and that person has insulin resistance, he will have to inject a lot more insulin to get the same effect as someone without insulin resistance. His cells will reject it, just as they do with natural insulin.

This is the same with someone not injecting insulin. When there is insulin resistance, the pancreas has to secrete much more insulin than is normal to clear the glucose out of the blood stream.
 
Hi @hichamgsm ,

In short. Exogenous insulin adds to the endogenous produced by the pancreas & increasing the chance of blood sugar being utilised by the cells.. (More keys to open the door!) it all does the same job..
 
But this means that this type will not benefit the use of insulin !!!
 
hichamgsm said:
But this means that this type will not benefit the use of insulin !!!
Click to expand...

No, not at all. The injected insulin does work, it just takes more of it. Just the same as you and I who don't need to inject insulin - if we have IR our pancreas has to produce a lot more insulin. This is what is bad for our health, likewise too much injected insulin.
 
hichamgsm said:
But this means that this type will not benefit the use of insulin !!!
Click to expand...

They will. The way I think of it is the pancreatic beta cells can only produce so much insulin. If there's insulin resistance, the body can't produce enough insulin on it's own to reduce blood glucose levels. Hence insulin injections to boost the amount in the blood. It may also be needed if there's damage to the pancrease, ie auto-immune problems meaning fewer beta cells, so falling insulin production.
 
Jaylee said:
Hi @hichamgsm ,

In short. Exogenous insulin adds to the endogenous produced by the pancreas & increasing the chance of blood sugar being utilised by the cells.. (More keys to open the door!) it all does the same job..
Click to expand...

Hi @Jaylee
Sorry for the inconvenience

Do you want to say that natural insulin needs external insulin to become effective ?
 
hichamgsm said:
Sorry for the inconvenience

Do you want to say that natural insulin needs external insulin to become effective ?
Click to expand...
No inconvenience at all, my friend.

Imagine trying to knock a bowling pin down with one ball? Then the increased chance of hitting the pin with more balls thrown at the same time...
 
Jaylee said:
No inconvenience at all, my friend.

Imagine trying to knock a bowling pin down with one ball? Then the increased chance of hitting the pin with more balls thrown at the same time...
Click to expand...
I understood what you meant thank you
But I personally think there is a defect in amino acids why not
Just guess I might be wrong
 
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