Hi
In general terms, if you have no microvascular complications and are overweight, the exenatide or sitqgliptin drugs should be a big consideration for you. Dennis' et al advice regarding diet is of course important.
Sitagliptin is an oral drug that works in a similar way to exenatide (injection). There seems to be very few people on it though it costs far less. It does not cause anywhere near the same amout of weight loss as exenatide. It also must be taken with other types of oral anti-diabetic drugs to have its maximum affect. Insulin will give a quicker control of A1C, probably more important if you have complications like me. But the weight gain is an almost universal problem (much like the glitazones). Exenatide ha a huge potential to affect type 2 outcomes, but it has only been in use a very short time. The 2-3 year effects seem to be maintained.
My diabetolgist is prescribing exenatide but has not used a gliptin yet. He has almost come round to giving it to me. Unfortunatley I have lost nearly 2 stone since Easter and last weeks A1c was 5.9%. By low carbing I have drastically reduced my bolus insulin use (20-50 units per day) but have stabilised my basal insulin (90 unit levemir). So he might feel I am too much 'off licence' to use exenatide. The American anecdotal reports seems to suggest that insulin exenatide users have a big fall in bolus doses and a much smaller reduction in basal doses of insulin.I am a bit more keen on sitagliptin than I was before
Just restarted the gym thsu week as well. Hopefully that might get some more weight off.