Personally I don't think it's possible to work out an exact ratio as there are too many variables to take into consideration - amount of exercise, illnesses, stress, weather, etc, etc, etc.
I stick to a specific ratio but will correct after an hour or so with insulin, exercise or carbs depending on which way the meter is swinging. I find timing the insulin shots in relation to what I have eaten or am about to eat is effective at keeping the BS spikes to a minimum.