I do find this fascinating, but I keep, personally, returning to the thought of "everything in moderation". We have seen runners at the London marathon die from drinking too much water. Humans cannot survive on 100% oxygen. If you feed lactose to my wife she is unaffected, yet I will be crippled for 24 hours, and yet she will be crippled by wheat, I will have raised BG, and my best mate, can eat it without a care in the world. My wife lives on caffeine. It makes me feel sick and light headed. We are each more unique than we sometimes like to admit, and whilst it is widely acknowledged cigarettes cause cancer, we've all heard of some who smoked all their lives without succumbing. Whilst many people obviously and justifiably believe sweeteners are the cause of their ailments, I don't believe there is anywhere near enough evidence to prove it categorically yet. I spent 18 months believing I was wheat intolerant, but it turns out, I am not, it was simply I happened to be eating wheat and milk on most days, because when I cut out cereals, I also cut out milk!