In my experience, yes.
Had 4.5-6.5 results for 3 weeks before surgery a couple weeks ago, now am having 7s, and 8s and a few 10+.
That is with insulin - trying to catch up but it proves a bit of hassle - have had infection etc, but only on/off fever so it's not superpredictable.
It a different kind of stress, I know, but stress hormones from anxiety etc can cause it to spike quite a bit. I know the SSRI 'flu', it's not pleasant - normally better to gradually reduce if possible as it can be quite stressful otherwise.
However, give it a bit of time and keep an eye on it, but don't fuss for a few days unless you get really high results (14+). If you do, then you need to be a bit more proactive. Otherwise I'd say keep doing what you know is right, and wait a bit.
-M