If you run often or long distances go to a running store that does gait analysis and get yourself fitted correctly. It's even more important for folks like us and even more important that you check your feet regularly.
Good running socks are also a good call as the are cushioned in the right place but also offer good ventilation and cooling.
If I get a blister, which thankfully is nt too often (touch wood!), I just pierce it once, squeeze out the fluid and apply vasilene so the skin of the bolster doesn't dry out and crack.
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