Dark and calloused knuckles

Diamond28 · Nov 16, 2017

Hi everyone. I noticed rough, calloused and dark skin on three of my knuckles long before my diagnosis. I Googled what it could mean and it was suggested that it could be a sign of diabetes. I am pre-diabetes and yet still got this symptom. As my diet improves and Ive lost weight, they are gradually going back to normal. Has anyone else noticed this symptom?

kokhongw · Nov 16, 2017

Yes. That is actually a sign of high level of insulin. There can also be darkening and thickening of skins around the neck, folds around various joints.

Moving to a insulin lowering diet will reverse that.

kokhongw · Nov 16, 2017

https://www.healthline.com/health/acanthosis-nigricans#causes4

Overweight people tend to develop resistance to insulin over time. Although the pancreas is making insulin, the body can’t use it properly. This creates a buildup of glucose in the bloodstream, which can result in high levels of both blood glucose and insulin in your bloodstream.

Excess insulin causes normal skin cells to reproduce at a rapid rate. For those with dark skin, these new cells have more melanin. This increase in melanin produces a patch of skin that’s darker than the skin surrounding it. Thus, the presence of acanthosis nigricans is a strong predictor of future diabetes. If too much insulin is indeed the cause, it’s relatively easy to correct with proper diet, exercise, and blood sugar control.

Dark and calloused knuckles

Diamond28

Newbie

kokhongw

Well-Known Member

kokhongw

Well-Known Member

Dark and calloused knuckles

Diamond28

Newbie

kokhongw

Well-Known Member

kokhongw

Well-Known Member

Privacy & Transparency

Privacy & Transparency