Whilst I agree with the majority of that statement, experimentation has shown a couple of other characteristics. Unfortunately, the duration of absorption is affected by the dose:I'm puzzled by that, though it might be the "semantics" that you are using.
The duration isn't affected by the dose, only the "peak amplitude" if you like (of the absorption curve). But if that "peak amplitude" is low, then as the absorption tails off, there is less "under the curve" to have any effect. But the time duration from end-to-end of the absorption curve is the same.
So there is a danger that, in order to have more "under the curve" towards the end of the absorption, the "peak amplitude" wil lbe too high and cause a hypo.
I've seen graphs like that before, which was what I was describing, and tbh if someone is making small adjustments of their dose, a graph like that is irrelevant. Basically, if they are injecting an amount down towards the lower end of the Y axis, they may as well not bother injecting anything, because there are far bigger variables going on in the body.
Well then, I'll assume, as I don't particularly want to read through 293 messages to find a statement that you are T1, that you are...You don't need to go to the Vatican to find out if the Pope is a Catholic. It is possible to click on someone's message count to see their messages (even when not logged in)
?they may as well not bother injecting anything, because there are far bigger variables going on in the body.
Quite. The only way you can really determine the answer is to test what's going on and determine yourself. There are usually multiple answers to a question and a number of ways to address the issue, and we can offer up the options that might help.Brilliant, thanks for your help all. I'll use some of the things mentioned and come back to you. It's probably the most annoying thing about internet forums when someone asks a question, it gets answered and then you don't know if it was the correct answer.
Thanks again
As the writer of the site says:You better tell the website person who wrote this then
http://www.diabetes.co.uk/blood-glucose/dawn-phenomenon.html
I've said before on this forum (whenever I decide to contribute) that there are multiple control systems in the human body, each with hormonal signal loops and/or nerve signals in the control loop, and they can impact one another in subtle ways.
In a non-diabetic, the control-loop for BG is fairly robust under "disturbance" inputs, but the treatment of T1 is an "open-loop" control. The whole ethos of treatment of T1 assumes that the "disturbance" inputs are known and un-changing from one 24-hour period to the next, and that once the diabetic has established his/her open-loop control method, any disturbances will be temporary. But this is completely untrue because, as well as continually changing short-term disturbance inputs, some longer-duration disturbances can creep in. It is this that can be frustrating, because when there is a change, it can take a long time to find out why, if ever. And sometimes, things just switch back to the way they were, because the disturbance input has changed again.
So if there is a rise in BG at dawn, if it becomes persistent, one has to think what has changed. It could even be as simple as something at work, that adds stress, which changes the amounts and timings of hormonal release, which in turn impact the timing and release of other hormones. In the non-diabetic, this might go un-noticed, or it might cause one to start waking up feeling less refreshed. But the T1 will notice changes, and a change in the dawn rise could be a result of something obvious that is being over-looked, or something less obvious that takes a while to suss out (if ever)
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