I eat late most days of the week, around 9pm. I have found that if my sugars are good around the 2 hour mark, they likely don't drop more then a point or so in the next 2 hours. So i try to go to bed around 7 mmol/L. Typically wake up around 6mmol/L
It can be worrisome, but there isn't any way around it besides 1) eat earlier, 2) stay up later so you can check 2 or 3 hours post injection, 3) eat a very low carb meal so you don't have to inject, or inject very little.
You could always try to eat like 10g of carbs more then you bolus for just before bed to ease your worrying, and see what your sugars are when you wake up?