GAD65 is an antibody that attacks and kills the beta cells in the pancreas which produce insulin. If you have these antibodies it means you more than likely have an autoimmune diabetes which will eventually lead to insulin dependence. The more antibodies you have the quicker this will happen! Hope this helps.
Diagnosed with GD in 2010, Completely disappeared postpartum. Re-diagnosed December 2012 with type 1.5 diabetes, age 26, BMI 23 currently controlled by only Metformin, 500mg twice a day.