When I started pumping, long before closed loop, I spent the morning up the hospital then went straight back to work, manual work, working with horses. We have so much more technology now than we did back then so I see no reason why you would need time off work. At some point you will have to go to work with your pump so why put it off a day. Your basals have to be set ( or set itself, depending on pump ) around your usual days work.
Just go for it and good luck, you will have teething problems but its worth it!