I have to say I left the set up to the pump team at the hospital. I took in details of all my current basal doses, carb ratios etc. I was also asked for an average of how many units I tend to take in a day. From that the pump team worked out some starting rates for the pump.
I have heard of several people who take "pump holidays" for a week or two, usually it seems to have been when people are going on holiday and want to be in and out of the pool or other activities where you'd probably want to be disconnected from the pump for more than an hour.
I can't see that it would work to stop pumping every weekend though. I've been told to allow a few days for the Levimir to be completely out of my system before I can fine tune the pump settings. Doing that every weekend would not make either pumping or MDI easy to deal with. I'd also say I doubt I would have got pump funding if I'd said I was only going to use it part time, they did need to see that people were committed to pumping.
Is there something you want to do at the weekends where a pump would be tricky? maybe there are some other solutions.