Hi,
This sounds like 'lipos' (lipohypertrophy). They can happen in anyone who tends to inject insulin into the same area all the time. The fatty deposits inhibit the absorption of insulin, which is why your hubby's BG went up. He will need to leave those areas well alone for some months before the fatty deposits break up, and obviously make sure he rotates his new injection sites, or he will get lipos there too. It is tempting to keep injecting into lipos because they tend to hurt less, but it's not a good idea from a BG control perspective.
Sue