A Dynamed summary on diabetes mellitus type 2 states that conditions affecting red blood cell lifespan may alter HbA1c levels [3]. HbA1c is decreased (falsely low) with conditions that shorten red blood cell lifespan such as acute or chronic blood loss, haemolysis, sickle cell anaemia, thalassaemias and hereditary spherocytosis [3]. However, HbA1c is increased with conditions that increase red blood cell lifespan such as iron deficiency anaemia, vitamin B12 deficiency, folate deficiency anaemia or splenectomy [3
NB I don't think when they talk about administration of B12 falsely lowering HbA1c they are talking about over the counter supplements either. The reference is to very specific cases when high amounts have to be administered..Patients with anemia due to deficiency of iron and vitamin B12 have high HbA1c levels. This can be reversed with administration of the deficient factor. In some cases, administration of iron and vitamin B12 can lead to falsely lowered HbA1c due to the preponderance of young erythrocytes in the circulation.[20]
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401751/?report=reader#ref20
I think she was right, I
Everything I can find suggests that a B12 deficiency falsely raises HbA1c. Treatment lowers it
NB I don't think when they talk about administration of B12 falsely lowering HbA1c they are talking about over the counter supplements either. The reference is to very specific cases when high amounts have to be administered.
You can find exactly the same info in table annex 1 here
http://www.who.int/diabetes/publications/report-hba1c_2011.pdf
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