Injection sites not working.

Sympathies for this complicated problem. What insulin regime are you on? What's your typical diet? I find that when my numbers are erratic, I can settle them down by cutting carbs.

I was told to inject in my buttocks which is the most fleshy part of the body

I get this too. sometimes I wonder whether I've injection water into my body instead of insulin. I can only inject into my stomach (have done for 20+years) and recently feel like nothing is going in. Ask my doctor who said my stomach is remarkable good and that o must but forgetting to inject? Let me know if you find a solution

Hi - I've been type ! for 28 years. Always well controlled (HBA1c 6.5). In 2017 (age 78 years) it got more & more difficult to control, with fluctuating insulin doses needed, steadily increasing to acheive the desired blood glucose result. I didn't find that there was any dependence on the injection site, my body just wasn't responding to the insulin.
Alongside this problem, I developed a 'pot- belly', adding approx.15kg to my weight.
The prognosis is that the cause is insulin resistance. This is increasingly recognised now as a pre-diabetes indicator. Fundamentally, the insulin is not getting into the cells and enabling the regular transfer of food out of the blood to feed the muscles. However, there does not seem to be any (published) research on this development in type I diabetics. My care team are completely flummoxed!
Does this sound as though it may be the root of your problem too?

I am a type I for 37 years and also inject into my stomach. Sometimes it doesn't reduce my sugar, and I chalk that up to insulin resistance. To remedy, I might get on the treadmill or stationary bike. Another thing that cuts resistance is metformin. I had to fight my doctors for decades to get a prescription for metformin. It had been a godsend.

I am at a computer all day and can't move around. That means that my insulin resistance stacks up. If I take a shot it might do nothing. But if I take it with metformin it will take effect. It's really helped my work. I am more productive now that I can correct my sugar without getting up and exercising to reduce the insulin resistance.

Are you aware of pooling? Maybe that's part of it. Stomach injections can form an insulin pool, and not enter the blood stream right away. Eventually it will be absorbed and can be released all at once, lowering blood sugar rapidly. What I do post-injection is massage and knead the area. I am trying to break up any pooling that may happen. I'm not sure it works but it makes sense to me so I do it. ;-)

My sugar spikes at night if I've been eating carbs. That's my liver dumping glycogen from its stores. To combat, I take a shot of NPH before bed. It smoothes out the spike so that I don't wake up with dawn phenomenon.