insulin cannot be heated or frozen, because it reduces its effectiveness, it is believed that the storage temperature of insulin is from +2C to +8С, and an unfavorable temperature is usually called above +30C or below 0C, but if you ask about the experience of this, then where I am sometimes there are frosts -30C and I sometimes carry insulin just in a bag or pocket (although I was taught to carry it in the inner pocket of a jacket closer to the body or in mittens), but I can give an injection after my insulin has been in such a cold. To be honest, I didn't notice any differences in efficiency, but maybe I was just lucky.