@Spiker , @tim2000s here's my latest draft post... on how to steer the metabolic boat.
Would love your thoughts.
https://www.dropbox.com/s/v0pxj84g5h6y9vd/The Goldilocks glucose zone.docx?dl=0
You are very welcome Marty and thank you for your great work and for taking the feedback in the constructive spirit that was intended!
Morning @martykendall, I've had a read through the goldilocks article this morning. I've a couple of observations that I'll type up when I'm not on a phone.
Intrigued to read your glucagon article. The various discussions on here led to me writing my own blog post linked to this topic. It's the first you'll come to if you follow the link in my signature.
Indeed it does, and I think we have to tread carefully in this respect. I can fully understand the perspective that Roger Unger has opened up based on my experiences of food consumption. I've started a debate with my diabetic team relating to Amylin and Glucagon, so it will be interesting to see where that one goes.Enjoyed your blog post @tim2000s
Yours covers overlapping territory to mine.
Certainly a minimally understood and challenging subject area.
It's been blowing my mind trying to understand it and debate it!
I think it's rather complex. Where a low carb meal, the fat just extended the time it took for the various glucose metabolism processes to take place.Tim would you say the fat affected the total insulin requirement, or just the timing?
Maybe this is why I have to allow approx 8 carb for an egg when I do my carb count calculations...protien..I love eggs and bacon etc but without allowing for the eggs my BSs spike.Total Available Glucose, a method for calculating insulin doses that uses protein and fat in the calculation as well as just carbs.
@Heathenlass, got more?
Thanks for posting this Indy. I'd not heard of Kraft. Another direction to read up in!Thought I would post this here as it's related to the whole subject of insulin/hyperinsulinemia.
Amazing blogpost by Ivor Cummins at the Fat Emperor Blog discussing the work of Dr Kraft, inventor of the insulin assay and his book on the Diabetes Epidemic. Fascinating stuff!
http://www.thefatemperor.com/blog/2015/9/7/kraft-summary-re-post-for-those-who-missed-it
Definitely worth watching the video as well.
Jason Fung comments on the Kraft insulin profile findings as well in this latest blogpost.Thought I would post this here as it's related to the whole subject of insulin/hyperinsulinemia.
Amazing blogpost by Ivor Cummins at the Fat Emperor Blog discussing the work of Dr Kraft, inventor of the insulin assay and his book on the Diabetes Epidemic. Fascinating stuff!
http://www.thefatemperor.com/blog/2015/9/7/kraft-summary-re-post-for-those-who-missed-it
Definitely worth watching the video as well.
Indeed it does, and I think we have to tread carefully in this respect. I can fully understand the perspective that Roger Unger has opened up based on my experiences of food consumption. I've started a debate with my diabetic team relating to Amylin and Glucagon, so it will be interesting to see where that one goes.
Reading your glucose/insulin/glucagon article, what stood out to me is that it doesn't pick up on the roles that insulin (and Amylin) have in suppressing Glucagon response and potentially why both T1 and T2 diabetics are more susceptible to GNG than non-diabetics as a result of Insulin resistance.
I've not yet found clear clinical studies relating to lack of satiety in Type 2 diabetics as a result of insulin and maybe amylin resistance (or maybe depletion as a result of high BG levels resulting in damage to the beta cells) but I think this is also linked in to the equation.
What I've also found is that by increasing basal insulin, I've been able to limit GNG caused by the (relatively) higher protein content of my diet. Now this could be down to one of two factors. Either a) It stops the liver undertaking GNG autonomously or b) it either regulates glucagon release or inhibits the reaction to glucagon in the liver and restricts GNG in the process. Either way, it has an impact, which is why I want to try Symlin (Synthetic Amylin) and see what the results are.
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