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Is the damage irriversible?

Sadly your initial assumption isn't quite right. The evidence is that if there is T2 in the parents there is around a 90% chance of it appearing as a hereditary condition in the children. For T1 it is somewhere between 40% and 70%.

The difference is that we can identify around 50% of the genetic markers for T1 and only 10% or so for T2.
 
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