Latest From Malcolm Kendrick

LittleGreyCat said:

https://drmalcolmkendrick.org/2018/08/21/what-cause-heart-disease-part-53-diabetes/

Fascinating insight into how elevated BG can damage a crucial component of the walls of blood vessels and increase Cardio-vascular risk.

I liked the term "atherogenic insults" - you blood vessel you!!

Meet the glycocalyx and enjoy.

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I know I'm going to enjoy this. See you on the other side.

Very interesting, indeed. So, as we thought, prolonged high bg levels and its concomitant insulin levels plus damage to glycocalyx = means it might be best not to become Diabetic. What I need to know now is if the damage is reversible.

My arteries should be slippery as eels instead they are scabby and full of weals....

What he has not addressed is why the arteries around the heart cop it more than any other artery. It is a problem that I gave some thought to when my sister had her fifth stent fitted. She puts half a salt cellar on her meals and I thought there might be a connection. I am now convinced that salt narrows the arteries.

The association with diabetes and CVD made me think that sugar might not be any kinder but why around the heart?

I have a half harsed engineering background and I thought of sand blasters. (Something is damaging the arteries but why the heart?). Most damage will occur when the speed and pressure of the blood is at its highest so if something in the blood is abrasive, maybe around the heart, since being next to the pump, the sand blasting effect was at its greatest.

Further down the arterial system the peaks of the pump might be less due to wide arteries being further away from the pump, like being further away from the rapids in a river. The calm venous system does not suffer from sand blasting because it is in the calm waters and a long way from the pump.

If your sister is salt sensitive and this increases her blood pressure then any damage to her 'pipework' by other means will be riskier e.g. being a smoker or a diabetic or both (hoping neither apply).
Note that diabetic damage occurs at both a macro and micro vascular level but has the most immediately fatal consequences in the CV system.

I don’t think it is just heart arteries that get affected.

I’ve heard of people withcalcification of the neck and leg arteries too. The problem could well be the size of the pipe. I mean, heart arteries are going to be much narrower and more easily obstructed than the bigger arteries.

NicoleC1971 said:

If your sister is salt sensitive and this increases her blood pressure then any damage to her 'pipework' by other means will be riskier e.g. being a smoker or a diabetic or both (hoping neither apply).
Note that diabetic damage occurs at both a macro and micro vascular level but has the most immediately fatal consequences in the CV system.

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She neither smokes nor is diabetic. The salt cellar does have to be re-filled every day so that attracted my attention.