in the blood stream are the red blood cells, which are made of a molecule, haemoglobin. Glucose sticks to the haemoglobin to make a 'glycosylated haemoglobin' molecule, called haemoglobin A1C or HbA1C. The more glucose in the blood, the more haemoglobin A1C or HbA1C will be present in the blood.
Red cells live for 8 -12 weeks before they are replaced. By measuring the HbA1C it can tell you how high your blood glucose has been on average over the last 8-12 weeks.
Pneu said:I can only speak from my experience but I think as long as you test regularly then using the above formula you are going to be reasonably close to your HbA1c... If you aren't then that would suggest a problem to me... i.e. you have a period of time where you aren't testing and you blood sugars are doing something odd?!! The one that springs straight to mind is that a lot of people test during the day but not many people test all to often at night! night-time is for instance 1/3 - 1/2 of your day where your sugars may be doing something you don't expect.
I am the first to admit that I am OCD / Anal about my resting regime and normally test at least once during the night (a five month old daughter helps here?!) this probably isn't for everyone but it may be worth picking a weekend night and setting your alarm for every 2 hours to see what those sugars are doing if you get a vastly different result
NewdestinyX said:There are a number of places where you can read how over trusting the HBA1c, especially for T1's, can not be telling the whole story. For example an A1c of 6.0 can be the 'average' of VERY HIGH numbers AND hypos which will even out to a 6.0. The person receiving the 6.0 could be giving themselves a pat on the back when they're still potentially doing a lot of damage to their bodies.
Monthly meter averages tell a better story in my opinion for the T2's. The reason for this is that some people have RBCs (red blood cell) lives that are shorter or longer than others. This will affect A1c in an 'overinflated' or 'underinflated' number where monthly meter averages are really telling the more accurate picture of your control regimen. The docs prefer A1c over meter log books for obvious reasons it seems to me. I agree meters can vary.. And because I know that my A1c isn't an averaging of lots of highs and hypos -- I actually chose my final meter that I use BASED on how close it matched/predicted my next A1c. I'm always within 0.1% on my next Lab A1c using the meter averages from the meter I use now.
For those interested. I've found the Freedom FreeStyle series of meters to be slightly inflated and the Walmart ReliOn Micro and Bayer AccuCheck to me a little 'under inflated'. I use the ReliOn CONFIRM and Bayer Breeze 2 and have found them to be spot on when their Monthly BG averages are compared to my Lab A1c. This also means I have pretty 'normal' Red Blood cell lifespan. If I didn't then such a tight tracking wouldn't be possible. That may be the case for several of you.
All meters in the UK now give plasma readings. Accuchek meters still gave whole blood readings until the end of last year when they changed their strips.I might be able to help here. First of all, the conversion from average bg to HbA1c depends on wether your bg meter is reading whole blood plasma or not. As I understand it, newer meters read whole blood plasma and older ones don't
Have a look at this graph.I'm also interested in how people came up with these equasions to get a likely hba1c from the meter averages but so far nobodys coughed that one up!
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