Micro Dosing Glycogen

Does anyone do what exactly? I seem to be missing something... can you expand on what you mean by glycogen micro-dosing? Google turned up empty handed (minus countless entries wrt psychedelic drugs) when I searched "glycogen micro dosing"

Grant

Do you mean Glucagon @Engineer88? I can't imagine why you'd microdose glycogen....

Edit: Yes, you do. I don't know of anyone who has done this. The main reason is that to mix up the glucagon you need to use all the water in the kit. Even if you only use a little bit of it, the life of the liquid is 24 hours then it becomes inactive. Sos you need to replace the whole lot. It's currently an issue in the Artificial Pancreas world. How to make long life, stable glucagon.

I 'd also not want to suffer the side effect of glucagon, even in a small dose, namely feeling really sick.

Do you mean glucagon?

Glucagon is the hormone (?) you can inject to tell the liver to release its stores of glycogen. I don't think glycogen exists as a medicine to dose with. (Someone needs to change one of these words because they are far too similar)

People do micro dose with glucagon. I have heard Stephen ponder, author of sugar surfing talk about it on the juice box podcast. But I wouldn't have thought it's common. Once you make up the kit you either dose it or you bin it. If you aren't hypo enough to need it, giving too much will force a liver dump, making you feel rough and increasing your risk of future hypos.

Wouldn't it be easier to eat something? Unless you are a non compliant child or suffering food poisoning? I think those are the situations ponder talks about - a kid who doesn't understand they have to eat the jelly baby etc.

Stick with jelly babies or a high carb drink.

If you find yourself requiring glucagon, then you certainly won't be doing this yourself.

Grant

Engineer88 said:

So I've been told that for a bad hypo I could inject 'some' of the orange glycogen kit which is kept refrigerated.

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Wouldn't that be a waste if your in a position to treat the hypo yourself

The time it would take to mix you could have downed some liquid glucose, besides if it was a really bad hypo would you be capable of mixing and injecting it yourself.

Engineer88 said:

So I should be a bit clearer yes I meant glucagon, silly iPad!

The reason I was asking was a seriously bad hypo for me last night. I did eat, then I had liquid glucose then Dex tabs and was still hypo. I was on a call with my partner and she wanted to call an ambulance because she wasn't that close to home. Thankfully I held off and eventually came up. I still feel pants today.

From the feeling I got at onset I wondered afterwards if I should have gone straight to glucagon. I had no one else to administer it and wonder if I took too much of a chance.

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Some hypos are a lot worse than others. But the easiest course of action would be to learn from what you bolused far too much insulin for and adapt to suit for next time? And if it was basal orientated then try to work out a reduced dose to avoid such a dramatic drop.

Grant

Engineer88 said:

It was neither. I have periods of hypos out of the blue with no corresponding changes such as bolus or basal. I also have no rhyme or reason to why these periods occur. They aren't set times apart or seasonal or hormonal and I've been through them on the forum in the past. It's an extreme sensitivity to insulin which resolves itself after normally a week or two.

It's like I'm producing some insulin but that's obviously impossible after 26 years

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That sounds awful, as if managing T1D wasn't hard enough - you've also got that hand grenade to deal with! You've never managed to get any useful info as to what this may be, why it's happening or found others who are experiencing it?

Grant

Engineer88 said:

Others sometimes have similar, I know @CarbsRok has similar. I follow all the 'rules' I understand my D, we rub along ok most of the time. But your hand grenade is Def the best description I've heard. It's almost as though my pancreas splutters like I said. Of course science says it's not possible but I've had 5 hypos in 24 hours. I've turned off basal for 2 hours last night completely and been on my lowest basal rate with temp reductions. I've also eaten more than I like to remember! Blugh!

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The reason I had problems was due to a very deep rooted infection eating into the bones under my eye sockets due to chronic sinus problems. Infection has been cleared under a GA. As I have Addison's disease glucagon is off limits.