Hi
That’s really interesting — thanks for sharing your experience! Sounds like Tirzepatide has done more for you than just lower blood sugar, the part about feeling more positive and having less inflammation really caught my attention, I’ve seen a few people mention similar things, but it’s great to hear a first-hand story.
I’m curious — how long did it take before you started noticing those changes (like mood or swelling improvement)? And have you had to adjust your food intake a lot since starting it, or did that happen naturally as your appetite changed?Thanks again for sharing — very encouraging to read!
The euphoria started a few days after my first 2.5mg jab. I was surprised it was so very quick, and strong, and I expected it'd be transitory. It is though, still with me 15 weeks later - I often feel the urge to laugh with delight, or whistle. It's nothing like being drunk, it's a sort of bubble of delight constantly just at the edge of awareness.
The swelling and inflammation in my calf, from the DVTs, was noticeably reduced after about a month or six weeks in. It has continued to get better, and the venous eczema has all but gone. My left leg is now only a couple of cm wider than my right, which is hardly visible, and it is a pale pink, instead of an angry red.
My atopic eczema has cleared up.
I do feel the cold much more acutely.
It has also played havoc with my INR. I take warfarin because of the DVT, and my INR shot up to 7. The interaction is obviously very new, and not well understood. I foind two case studies, one in which the INR dropped, during tirzepatide, and one where it got up to 9 and the pstient died.
My blood pressure has been dropping fairly consistently, down to healthy levels, mainly.
Oh, I've almost stopped drinking. We had enjoyed a bottle of wine together about once a week, but now, after a big glass of wine, I feel quite unpleasantly drunk, slurring words, staggering, drunk, and nauseous. I have found that cider, which is less than half as strong [5% vs. 14-16%], mixed with kombucha (yes, it sounds horrible, but doesn't taste too bad), half-and-half, getting the ABV down to ~2% allows me to have a few glasses, with my wife, before I have to go and lie down.