Hi,
I have read your post but my reply is basically based on the title of the post. I have had peripheral vascular disease for many years now. It started with the neuropathy and also areas that became numb. When it first started I was told that because the main blockages were below my knee, angioplasty was not possible. Since then angioplasty has been developed further and it has become possible to perform it right down to the ankle. I had this done last year when 2 of my toes started to change colour and become cold and painful. The surgeon that performed it is, in my opinion (and that of very many others), one of the worlds leading vascular surgeons. He was completely happy to do the job on my right leg but at the same time, even though I offered to go privately with him, he refused to do the same to my left leg. This was because he believes that doing the surgery before it is needed can produce more negative effects than positives. As you mention, the smaller vessels that may not currently be blocked can suffer from the movement of the blockages and again, at the present time, these cannot be cleared.
My angioplasty was only successful in clearing the blocked vessels for about a month. The surgeon then performed a "popliteal-to-distal" arterial graft and amputation of the toes because the small vessels had become blocked following the angiogram. Eventually my lower leg had to be amputated.
I really don't believe that I would have kept my leg whether the angioplasty had been done or not but I think I probably had longer using it because the angioplasty was done later rather than sooner. I think that in some cases the damage has been done before the neuropathy and pain is noticed, so what ever is done afterwards to "prevent" the problem is likely to be too late.