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Statins are getting a Makeover

Oldvatr

Expert
Messages
8,453
Type of diabetes
Type 2
Treatment type
Tablets (oral)
Announced today in the news. statin makers are applying for FDA approval for the Polypill, which is basically a statin combined with another medication. The one they are putting forward has either a BP med or Aspirin. These are fixed dose medications.

The application is for the general public at large and their claim is that a single polypill reduces the risk of heart attack by 25% I hope they produce one that combines statin with a laxative, to reduce the effect of all this bull effluent.

Polypill - an overview | ScienceDirect Topics

www.sciencedirect.com

I think it is reasonable to say that most of us using these medications as seperate meds find that we often need to chop and change dosage and/or brand and /or drop one until we find a solution that suits us. So the polypill cannot cope for individuality.
 
Scares the bejasus out of me. People might not die of this or that condition, but they are very likely to die from the numerous side-effects of polypharmacy.

At least with taking individual pills, one can see if stopping one gets rid of any side-effects that alarm us.
 
It still wouldn't impress me enough to take it
 
'New drug' new patents?
 
Robbity said:
They can push their fancy new polypills all they like - but it won't be down my throat...
Click to expand...
Its bad enough with Bp meds, finding something which has no side a effects or actually works. and at the same time swerving statins which is recommended by the GP. No chance on a polypill, they can put them where the sun doesn't shine
 
This is ridiculous... at least I know I cannot take polypill in the future - can't take NSAIDS.

Not going to take any statins meds either.
 
I would not be taking it.And what if they try and force people to take it.Say if it was to prevent maybe 4 different
Conditions. high blood pressure etc etc and you had 2 of them already. Maybe they would say 'Cut it in half then'.
'Saves us time.
 
Hi,

I have no markers for any cardio issues. But being a “gentleman of a certain age” get offered them at every opportunity.
One locum at a med review was so bold & even suggested (outright.) I could die in the next 10 years if I didn’t take them..?! (This has been pushed my way since I hit 45?)

So now the analogy. I sprinkle “anti-elephant powder” around the perimeter & on the lawn of my property every evening before I retire to bed. Am I guaranteed to open the curtains in the morning & not see my borders trashed..
 
Clever since nobody will be able to pin down what's caused the side effects and if it doesn't work you can increase dosage (see statins, diabetes drugs and oxycontin). I bet if they can alter metformin by a molecule or 2 they can add that one in and market it to those suffering from metabolic syndrome. (Mod edit) there's a big market out there. I bet you guys know lots of people who would buy it over the counter already!

edit : deleted content to comply with forum ethos and rules
 
Last edited by a moderator:
I find it interesting which meds are pushed remorselessly and which are refused equally remorselessly. For instance, in the days when in desperation I went for a private thyroid test which confirmed low thyroid, my GP refused to send me for a full thyroid test, and of course I wasn't in low thyroid readings with the blunt instrument test he allowed. He also would not prescribe antibiotics after a recent post-surgery infection issue, and yes I do understand the concerns about antibiotic resistance, but in this case they were justified and the recommendation came from the surgeon. Previously, I hadn't had antibiotics for around 20 years, so it isn't as if I'm always asking for them. However he is as remorseless about prescribing statins as I am about refusing them. It is very tempting to be cynical about this.
 
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