At risk of developing CVD’ means people who have a 20% or greater 10-year risk of developing CVD as estimated by an appropriate risk calculator, agreed by local clinicians, or after a clinical assessment to estimate CVD risk when an appropriate risk calculator is not available, for example, in older people, people with diabetes and people in high-risk ethnic groups.
http://www.nice.org.uk/nicemedia/pdf/TA094guidance.pdf'When the decision has been made to prescribe a statin, therapy is
usually initiated with a drug with a low acquisition cost.'
'the acquisition cost of simvastatin listed in the NHS Drug Tariff (July 2005) is
£1.65 for 28 x 10-mg tablets, £1.48 for 28 x 20-mg tablets, £3.57 for
28 x 40-mg tablets, and £20.29 for 28 x 80-mg tablets. Costs may vary in
different settings because of negotiated procurement discounts.' *
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