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Metformin and Stomach (not bowel) issues?
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<blockquote data-quote="Indy51" data-source="post: 634564" data-attributes="member: 48386"><p>I started on the metformin in January and by June was having all the problems of stomach pain, other digestive upsets (mostly all upper GI) and tested low for iron. Had the endoscopy in early July. They wanted me to take Nexium for acid blocking, but within a couple of days I was having all the GI symptoms I used to have before going gluten/grain free, so stopped taking it. I've read speculation on some celiac forums that taking a PPI long term can cause gluten sensitivity. Once I stopped taking metformin (and Nexium), the stomach pain resolved itself within a few weeks. I also had a series of 5 ferritin injections and next time I was tested the blood levels were fine again. My B12 was fine but when I mentioned the effect metformin has on it, my GP said "it's not on the list", so I try to mention it to anyone who has been on the drug for a while.</p><p></p><p>BTW, taking PPIs long term can cause all sorts of malabsorption issues, with B12 being the major one. I was on them for 9 years prior to my Type 2 diagnosis and blame them for completely destroying my digestion <img src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" class="smilie smilie--sprite smilie--sprite14" alt=":arghh:" title="Arghh :arghh:" loading="lazy" data-shortname=":arghh:" /></p></blockquote><p></p>
[QUOTE="Indy51, post: 634564, member: 48386"] I started on the metformin in January and by June was having all the problems of stomach pain, other digestive upsets (mostly all upper GI) and tested low for iron. Had the endoscopy in early July. They wanted me to take Nexium for acid blocking, but within a couple of days I was having all the GI symptoms I used to have before going gluten/grain free, so stopped taking it. I've read speculation on some celiac forums that taking a PPI long term can cause gluten sensitivity. Once I stopped taking metformin (and Nexium), the stomach pain resolved itself within a few weeks. I also had a series of 5 ferritin injections and next time I was tested the blood levels were fine again. My B12 was fine but when I mentioned the effect metformin has on it, my GP said "it's not on the list", so I try to mention it to anyone who has been on the drug for a while. BTW, taking PPIs long term can cause all sorts of malabsorption issues, with B12 being the major one. I was on them for 9 years prior to my Type 2 diagnosis and blame them for completely destroying my digestion :arghh: [/QUOTE]
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