Hi After much deliberation, of Endo putting me on metformin doctor taking me off and nurse putting me on it I was told to take 2,000 mcg metformin to be built up over the first month. I have been on the full dose since last Saturday and feel sick most of the time. When I try to eat I can only manage three or four mouthfuls.My question is can metformin do this, or is there a possible underlying cause. I have chronic kidney disease stage three and although I reminded the nurse of this she looked at my results and said it wouldn't be a problem. I am not quite sure what to believe any more at our practice so I thought maybe you guys might have any advice. Many thanks