From what I've learned is that there are usually autoimmune conditions clusters in the family over all.
Having this vunerablity to autoimmune conditions is surely to at genetic level but inheriting T1 itself is incredibly tiny in terms of probability.
I have two T2 parents (the only confirmed T2s, this has high hereditory factors esp in S.East asians which are 6 times more likely to get it if parents have it) however I'm S.east asian and yet I'm 'LADA' or adult onset T1 and no one else has it :crazy:
In my family some autoimmune conditions include rheumotoid athritis, virtiligo, thyroid, hay fever, as examples. On top of that other things e.g we have thalassemia B deficiency (this is genetic) we have asthma (is this autoimmune? I'm unsure), dermatological problems, alopecia, PCOS, Endometriosis, neurological heart issue (my sister recently, the other being tested) vit D deficiency (my brother recently - he also had an op for double carpal tunnel) the list goes on and on and on...
Out of curiosity is there any other autoimmune conditon around your family?
From what I've learned is that there are usually autoimmune conditions clusters in the family over all.
Having this vunerablity to autoimmune conditions is surely to at genetic level but inheriting T1 itself is incredibly tiny in terms of probability.
I have two T2 parents (the only confirmed T2s, this has high hereditory factors esp in S.East asians which are 6 times more likely to get it if parents have it) however I'm S.east asian and yet I'm 'LADA' or adult onset T1 and no one else has it :crazy:
In my family some autoimmune conditions include rheumotoid athritis, virtiligo, thyroid, hay fever, as examples. On top of that other things e.g we have thalassemia B deficiency (this is genetic) we have asthma (is this autoimmune? I'm unsure), dermatological problems, alopecia, PCOS, Endometriosis, neurological heart issue (my sister recently, the other being tested) vit D deficiency (my brother recently - he also had an op for double carpal tunnel) the list goes on and on and on...
Out of curiosity is there any other autoimmune conditon around your family?
If you mean that a lot of your family has red hair, this is interesting, as when i went for celiac tests - as there is a lot of autoimmune disease in the family and i had certain symptoms - they commented on the very slight red in my hair, asked me about my family red hair history - 3 in the family had pure red hair - they then asked where that side of the family originated - East Scotland - and they said Celtic genes were thought to be linked with autoimmune disease. The tests were negative but it got me thinking - the red haired family members did not develop autoimmune diseases - but quite a lot of some of their descendants have - could this be a co-incidence, what has happened in other families with red hair?In my family T1 diabetes is as common as red hair! My mother (63 years now on insulin) her brother (again over 60yrs) me, two cousins and another cousins son. When I was diagnosed 26 years ago the doctor suggested there was no hereditary link.
Can I be nosy and ask if you have diabetes in your family? Do you have siblings/parents etc with Type 1 as well as yourself?
I was diagnosed during my first pregnancy at 29 weeks. My younger brother was diagnosed T1 6 months after me!
I also have a first cousin (on my father's side) with T1 and my father is T2 (although I have been told that this should have no bearing on us)
I just wondered your thoughts on it being genetic?
Yes , just like I stated it is the immune response that is genetic not the actual "genes" . If they can figure out how to disable the response that would be awesome .Looks like it may be - but in a complex way - just seen this http://medicalxpress.com/news/2015-07-diabetes-patients-blood-proteins-immune.html.
It would be - i am not a scientist, but it looks as if this line of research might just be very hopefulYes , just like I stated it is the immune response that is genetic not the actual "genes" . If they can figure out how to disable the response that would be awesome .