Recent Content by Lilak

Hope your side effects ease. I had no option but to drop out, skin sagging where it was muscle before I started the trial (I have also recently had a total knee replacement, and leg muscles diminishing hasn't helped with recovery exercises), and not wanting to eat regularly isn't the ideal...

Hi, No, they were still bad. So I made the difficult choice to cut down to a tablet every other day for a week, then come off altogether. Main reasons for coming off were the symptoms weren't getting any better, and (more importantly) the rapid weight loss. I'm a retired firefighter, and have...

I'm sorry you have been given the placebo, especially as the run-in tablets were doing you good with your blood glucose (HbA1C) levels. I've come off the Semaglutide for a while now, having lost just over 15kg since I started, and am looking very gaunt. Now I need to build my muscles up to get...

Hope yours goes well. Before you go in, make sure your quads are in good shape, as they will be crucial to a quick recovery. Also, work on your straight leg raises, as these will be hard for the first couple of weeks after surgery, but don't worry, it is normal, and you'll get there once the...

Hope all goes well with the knee replacement. I have just had my left knee replaced (just over 10 weeks ago) and the weight loss helps with the recovery, although my leg muscles need a lot of work as they too have diminished. I had cartilage implant on my right knee in 2011 (was told it would...

Definitely have a bitter taste, and along with the other symptoms, I am positive I am on the Semaglutide.

Had blood tests last week, HbA1C is now down to 34, so a massive drop, and confirms I am on Semaglutide and not the placebo. Also, have lost just over 12kg since I started the trials, and wife says I am looking gaunt. She's also worried because I have lost a lot of muscle tone. I am constantly...

Just started my 3rd bottle of the randomised tablets. Still got reduced appetite, and losing weight (lost just under 9kg since I started on the trials). So I am convinced I am on the Semaglutide and not placebo, will find out when I have my next HbA1C in about a month.

Are these the randomisation tablets? If so, I think you may be on the Semaglutide and not the placebo, and your body may just be settling into the medication. I have had a quick look at the trial documentation, and it confirms that once you start the randomisation stage, you will remain in the...

I believe once you start on the randomised tablets, you will stay on whatever you were given (either Semaglutide or the placebo) as otherwise they cannot measure the outcome of the trial. And yes, the trial is for 5 years, but you can opt out whenever you wish, or if your prescription...

I first suffered with severe leg cramps about 6 years ago, and my then GP prescribed Quinine Sulfate, whilst warning me of the side effects, so it might be worth doing a bit of research before seeing your GP. I last suffered with leg cramps 2 years ago, and when I spoke to my current GP, I...

2 weeks into the Randomised tablets. I think I am on Semaglutide, not the placebo. Lost another 1kg in weight. Appetite is still suppressed. An hour after taking the tablet, can't face a morning cuppa or toast (feelings of nausea) so it isn't until late morning or early afternoon before I have a...

Just checked, my HbA1C results are back, now BG levels are at 42 mmol/mol, so just outside non-diabetic range of 20.0 - 41.0 mmol/mol. That is down from 45 mmol/mol a month before starting on the first run-in course (the 3mg tablets). Will see if that changes on the next blood test in 3 months...

Yes, don't try to do a 'catch-up' (the instructions state you can still take it the same day *if you have not eaten anything for at least 6 hours AND have not had anything to drink or taken any oral medication for at least 2 hours*, wait at least half an hour after taking the study tablet before...

I too had an invitation letter, did my questionnaire online, and was accepted. As already mentioned, it wouldn't hurt to contact Ascend, and ask if you meet the requirements for the trial, and if so, whether you could be considered to take part. Good luck.