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I may contact the Ascend+ team myself as I find the 14 mg pretty nauseating ( literally ) and constipating. What has helped me is to take Fybogel morning and evening and that has eased my constipation - I will cut back to one sachet per day. when jhabits become more stable.

I've just started my second box of 7mg so still on the run-in. I think randomisation happens on the first tablets send after the initial ( 28x3.5 &56x7 ). Originally I was quite nauseous and off food ( my wife said it was like the was when pregnant ! ), but now generally comfortable but...