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  1. J

    Anyone on the Ascend Plus trial?

    They are very bitter - but a good Placebo should match with a bitter flavour. I would not rely on taste to be certain !
  2. J

    Anyone on the Ascend Plus trial?

    I found the run-in OK and noticeably effective. I eventually found the 14mg dose was to powerful for me - no way was it a placebo. I lost over 10% of my body weight. I asked the Ascend team to put me on 7mg - which they might have done - although I now suspect that I am on Placebo 7mg. My...
  3. J

    Anyone on the Ascend Plus trial?

    I may contact the Ascend+ team myself as I find the 14 mg pretty nauseating ( literally ) and constipating. What has helped me is to take Fybogel morning and evening and that has eased my constipation - I will cut back to one sachet per day. when jhabits become more stable.
  4. J

    Anyone on the Ascend Plus trial?

    I've just started my second box of 7mg so still on the run-in. I think randomisation happens on the first tablets send after the initial ( 28x3.5 &56x7 ). Originally I was quite nauseous and off food ( my wife said it was like the was when pregnant ! ), but now generally comfortable but...
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