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My sympathy too! Shortly after beginning 10mg daily of Dap I developed balanitis which then moved to UTI followed by bladder infection and had multiple antibiotic courses to get rid! Should have taken more care to keep clean & dry. Now reaping the rewards as now 6.7mmoiL average and pre-...

5.9 this morning

Checking up reminded me, on the small doses I did have constipation but that has slowly gone away since being on the 14 mg dose.

Thanks, I'll give it a try

No!

Now nearly 2 months into Randomisation.. feeling more hungry and less nauseous so I suspect that I'm on the placebo. Still losing weight slowly, 10 kilos over the whole trial so far. Blood glucose varies between 5 and 9. Was able to reduce Metformin to two tablets a day so good news there too...

2 months in to Randomisation. Not so nauseous and more hungry so probably placebo but still losing weight but very slowly. 10 kilos lost over the whole trial so far!

I am now on the 7mg having completed the 1st 3gm bottle, still on the run-in -- I find it very odd that you are not feeling any side effects. In your shoes I would telephone the Ascend helpline (number in the leaflet) and see what they say? Pleass do tell us the response?

Hi Bongos, for myself I have felt slightly nauseous, mildly constipated from the outset and plus feeling very full and up to now lost almost 6kg - so my experience is very different to yours! I have also discovered that a Ginger shot helps with both nausea and satiation as well as tasting amazing!

Thanks for the advice..still smaller meals is doing the trick and I am now becoming accustomed to the 7mg dose. I find that a minimum of half a large glass of water with the pill appears to reduce the immediate feeling of being satiated immediately. Weight down nearly 3kg now.

Well done Growler, perseverance paid off and you have given me hope for which I thank you. For those suffering from constipation I found that a stool softener such as Dulcoease worked for me with a very low dose after the initial course -- follow the instructions. Have lost half a kilo so far...

Started "Run In" a week ago -- no problems other than slight nausea and feeling "full" plus occasional constipation