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I would describe myself as nothing more than an occassional social drinker but since going to randomisation i can barely manage two pints of Guinness or ale. Simply too full. I assume that is to be expected?

Well that is interesting. I am minded to think any bitterness or lack off with the pill could be misleading. It could be that your body has quickly adjusted to the real drug hence the return to pre-trial normality. I guess each individual will have different feelings.

Perhaps the mind plays tricks but I am convinced I am on the real thing albeit the randomised pill doesn't taste bitter. In essence my side effects have elevated since i went to 14mg a week ago. One assumes that wouldn't be the case with placebo?

I suspect people will think its naive but the placebo effect shouldnt be dismissed or understated. Even those on this can maintain good habits from the early stages of the trial.

Wishing you well with it this time around. There is denying that this is a challenging trial in the first few months. Try different eating patterns to minimise the discomfort. From my experience it is absoloutely imperative to ear much smaller meals than previously.