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“Rapid-acting” insulin taking hours to work…
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<blockquote data-quote="StewM" data-source="post: 2430142" data-attributes="member: 538114"><p>I don't per se have advice, but I will share my experience which is similar.</p><p></p><p>In February/March, I was moved onto Fiasp. March-May I was getting great results. Fiasp was working about 50% faster* than my Humalog. However, things started to change in June (around when the weather got HOT), from that point on I've noticed the Fiasp get slower and slower. It's still getting slower now in August. At the moment, the Fiasp is now 100% slower than the Humalog**.</p><p></p><p>Another observation is the Fiasp now seems incredibly tied to activity levels. For instance, if I have lunch at my desk and work for a couple of hours I might as well have taken no Fiasp at all. Whilst inactivity affects all Insulin the difference between Fiasp when coupled with inactivity and other Boluses is much much more profound. If I was to take Insulin, eat Lunch then go for a fifteen-minute walk back to my office, then work for two hours, I'd get normal in-range results. However, if I was to do the same as the last example, but after an hour of sedentary work, I discovered I need to go out and get something, meaning a brief walk and back (totalling 15 mins), not only would I run the risk of going low, but my Blood Sugar would keep going low*** over and over again for hours. Again, whilst needing less Insulin whilst active is normal, the profound effects of a minimal level of activity is highly unusual compared to other Insulin. </p><p></p><p>*For example, if I needed to pre-bolus by 10 mins, I'd now only need to pre-bolus by 5 mins. </p><p></p><p>**For example, if I needed to pre-bolus by 15 mins, I'd now need to pre-bolus by 30 mins.</p><p></p><p>***Treatments of the Lows would work as per Hypo guidelines but then after 30-60 mins of stability, my Blood Sugar would crash down again.</p></blockquote><p></p>
[QUOTE="StewM, post: 2430142, member: 538114"] I don't per se have advice, but I will share my experience which is similar. In February/March, I was moved onto Fiasp. March-May I was getting great results. Fiasp was working about 50% faster* than my Humalog. However, things started to change in June (around when the weather got HOT), from that point on I've noticed the Fiasp get slower and slower. It's still getting slower now in August. At the moment, the Fiasp is now 100% slower than the Humalog**. Another observation is the Fiasp now seems incredibly tied to activity levels. For instance, if I have lunch at my desk and work for a couple of hours I might as well have taken no Fiasp at all. Whilst inactivity affects all Insulin the difference between Fiasp when coupled with inactivity and other Boluses is much much more profound. If I was to take Insulin, eat Lunch then go for a fifteen-minute walk back to my office, then work for two hours, I'd get normal in-range results. However, if I was to do the same as the last example, but after an hour of sedentary work, I discovered I need to go out and get something, meaning a brief walk and back (totalling 15 mins), not only would I run the risk of going low, but my Blood Sugar would keep going low*** over and over again for hours. Again, whilst needing less Insulin whilst active is normal, the profound effects of a minimal level of activity is highly unusual compared to other Insulin. *For example, if I needed to pre-bolus by 10 mins, I'd now only need to pre-bolus by 5 mins. **For example, if I needed to pre-bolus by 15 mins, I'd now need to pre-bolus by 30 mins. ***Treatments of the Lows would work as per Hypo guidelines but then after 30-60 mins of stability, my Blood Sugar would crash down again. [/QUOTE]
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