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3rd person in my family has been diagnosed with type 1
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<blockquote data-quote="Orchid" data-source="post: 47952" data-attributes="member: 13727"><p>Hi there</p><p></p><p>Just to let you know a bit about our family.</p><p></p><p>My Dad was diagnosed (aged 18) back in the 1950s with type 1. Since then, myself diagnosed aged 9, my brother age 9, my son age 9, my daugter age 9 and my neice (my brother's daughter) was diagnosed age 10. - That's 6 of us altogether.</p><p></p><p>When my daughter was diagnosed in April 2008 - the possibility of MODY was mentioned. I had blood tests done and they were sent down to Exeter University where the MODY diabetes research is being done. They tested for the gene mutation HNF1alpha and HNF4alpha - 2 of the MODY types.</p><p></p><p>I was really excitied about this as if they had found either of these gene mutations in my blood, there was a chance that the diabetes team would consider starting my daughter off on a sulphonylureas tablet - we had caught her very early and she was still producing much of her own insulin at that time. Unfortunately both the tests came back negative they did not find either of these gene mutations and therefore the team would only treat my daughter as a type 1 and she had to go on insulin.</p><p></p><p>It seems obvious to me that we must have some kind of genetic type of diabetes, but as yet it is not known. If anyone can shed any further light on this subject for me, I would be most grateful.</p><p></p><p>Kind Regards</p><p>Orchid</p></blockquote><p></p>
[QUOTE="Orchid, post: 47952, member: 13727"] Hi there Just to let you know a bit about our family. My Dad was diagnosed (aged 18) back in the 1950s with type 1. Since then, myself diagnosed aged 9, my brother age 9, my son age 9, my daugter age 9 and my neice (my brother's daughter) was diagnosed age 10. - That's 6 of us altogether. When my daughter was diagnosed in April 2008 - the possibility of MODY was mentioned. I had blood tests done and they were sent down to Exeter University where the MODY diabetes research is being done. They tested for the gene mutation HNF1alpha and HNF4alpha - 2 of the MODY types. I was really excitied about this as if they had found either of these gene mutations in my blood, there was a chance that the diabetes team would consider starting my daughter off on a sulphonylureas tablet - we had caught her very early and she was still producing much of her own insulin at that time. Unfortunately both the tests came back negative they did not find either of these gene mutations and therefore the team would only treat my daughter as a type 1 and she had to go on insulin. It seems obvious to me that we must have some kind of genetic type of diabetes, but as yet it is not known. If anyone can shed any further light on this subject for me, I would be most grateful. Kind Regards Orchid [/QUOTE]
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