About Dodgy Blood and Meter Accuracy.

BloodThirsty

Well-Known Member
Messages
157
I have been pondering how different glucometers produce dramatically different results. Whilst there is usually an acceptable level of consistency between the daily readings of each, why might there be a difference in excess of 1.2 mols between one and t'other?

For instance, my FBG might be 5.2 mmol/l with one unit (a celebratory result) and 6.4 with another (well inside the pre-diabetic range).
Fortunately, I have a GlucoRx HCT meter that not only displays blood glucose, it simultaneously gives a hematocrit % reading and applies hematocrit correction.

From Wikipedia, hematocrit is the volume percentage of red blood cells in blood and is normally 47% ±5% for men and 42% ±5% for women.
Now, mine is all over the place, falling between 24 and 41 but the good ol' GlucoRx gives predictably consistent results irrespective of my HCT. Unfortunately, the same can't be said for my other units which are all relatively state-of-the-art yet about as accurate as a blind nail thrower.

Clearly, this might be a problem that is specific to those like myself with low hematocrit levels, but the following paper that examines this issue shows the considerable influence that HCT can exert on glucometer readings:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692232/

One can examine the individual graphs to see why only 6 out of 19 meters tested were relatively unaffected by HCT. Ah yes, I do realise that the study is 5 years old but the meters I have are all considerably younger.
 

Phoenix55

Well-Known Member
Messages
576
Type of diabetes
Prediabetes
What I find worrying is that the finger prick test is fine for T1 to use for working out how much insulin to inject beyond their basal yet it is not accurate for T2 - only an HbA1c test is regarded as being of sufficient accuracy, regardless of the margin of error inherent in testing or if the patient has a slightly different length of life of red blood cells. The logic leaves a bit to be desired.
 

Mr_Pot

Well-Known Member
Messages
4,573
Type of diabetes
Type 2
Treatment type
Diet only
What I find worrying is that the finger prick test is fine for T1 to use for working out how much insulin to inject beyond their basal yet it is not accurate for T2 - only an HbA1c test is regarded as being of sufficient accuracy, regardless of the margin of error inherent in testing or if the patient has a slightly different length of life of red blood cells. The logic leaves a bit to be desired.
The finger prick test is a measure of the current glucose in blood, which is what a T1 needs to know to decide how much insulin to inject at that time. A finger prick test does not give the average blood glucose which is what is required to diagnose T2 or measure the degree of control.
 

jackois

Well-Known Member
Messages
391
Type of diabetes
Type 1
Treatment type
Insulin
As a type one, using both finger prick testing for driving and calibrating the dexcom G5 CGM , I've learnt to take it all with a pinch of salt.

The other day, not believing the CGM reading, I meter tested, got a higher reading than expected, rewashed my hands, re-tested with a different finger, got an even higher reading & on a third finger got a lower reading than I thought it was. This can be a regular occurrence...

Another day every reading can match... I haven't a clue why...