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<blockquote data-quote="Oldvatr" data-source="post: 1265234" data-attributes="member: 196898"><p>Yes but here's another principle. It costs a bucket load of money to get that proof. Even when a philanthropist such as Bill Gates or Mark Zuckerberg provide funding, they get pilloried for having hidden and dark motives for doing so. In general only drug companies who will eventually benefit from selling a successful product will put up the cash. and it is this that leads to the corruption that we are suffering from today.</p><p></p><p>If every body paid a tithe towards funding medical research then we would have no excuse for providing poor evidence or for cooking the books. We already pay National Insurance that was originally to provide this type of social funding, so why not lobby the PM to double this tax? Do you think that might work?</p><p></p><p>I have already listed medicines that have come out of the closet to join the ranks of officially proven medicines, so I wil add a few treatments that have also recently become mainstream. Leeches and Maggots. </p><p></p><p>In mediaeval days, wounded soldiers used to **** on each others wounds to prevent infection. Now we use urea based products as skin care treatments, and sulfonylurea drugs for treating diabetes. We use ammonia derived from that same useful stuff as a domestic cleaner. Many of these products were 'invented' within my lifespan. </p><p></p><p>I wonder how many of these products went through proper double blind RCT testing on humans before being licenced? Only the sulfonylureas, I bet. The Ebola vaccine was released for use on humans without having formal tests, and it worked. But it was derived from jungle juice mixed up in a lab somewhere and only tested on animals and invitro trials, But it was not a formal medicine with full track safety record, and we still don't know what long term risk there may be. I mean Larium had better track record and its been withdrawn for long term problems. So RCT trials do NOT give a guarantee that the med works or is safe. Actos and Avandia had full RCT trials and became official meds (for a while).</p></blockquote><p></p>
[QUOTE="Oldvatr, post: 1265234, member: 196898"] Yes but here's another principle. It costs a bucket load of money to get that proof. Even when a philanthropist such as Bill Gates or Mark Zuckerberg provide funding, they get pilloried for having hidden and dark motives for doing so. In general only drug companies who will eventually benefit from selling a successful product will put up the cash. and it is this that leads to the corruption that we are suffering from today. If every body paid a tithe towards funding medical research then we would have no excuse for providing poor evidence or for cooking the books. We already pay National Insurance that was originally to provide this type of social funding, so why not lobby the PM to double this tax? Do you think that might work? I have already listed medicines that have come out of the closet to join the ranks of officially proven medicines, so I wil add a few treatments that have also recently become mainstream. Leeches and Maggots. In mediaeval days, wounded soldiers used to **** on each others wounds to prevent infection. Now we use urea based products as skin care treatments, and sulfonylurea drugs for treating diabetes. We use ammonia derived from that same useful stuff as a domestic cleaner. Many of these products were 'invented' within my lifespan. I wonder how many of these products went through proper double blind RCT testing on humans before being licenced? Only the sulfonylureas, I bet. The Ebola vaccine was released for use on humans without having formal tests, and it worked. But it was derived from jungle juice mixed up in a lab somewhere and only tested on animals and invitro trials, But it was not a formal medicine with full track safety record, and we still don't know what long term risk there may be. I mean Larium had better track record and its been withdrawn for long term problems. So RCT trials do NOT give a guarantee that the med works or is safe. Actos and Avandia had full RCT trials and became official meds (for a while). [/QUOTE]
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