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<blockquote data-quote="smidge" data-source="post: 224027" data-attributes="member: 29301"><p>Hi Mishigato!</p><p></p><p>Not sure if you've understood LADA properly? It is a form of Type 1 diabetes - it is a slow onset type and is sometimes called Type 1.5. It is generally diagnosed via a GAD antibody test. However, the problem is that while testing positive for GAD antibodies means you have the autoimmune form of diabetes, testing negative is inconclusive - it does not rule out LADA. Now, if you are being put in the LADA box, Gliclazide is probably not the best choice of drug. Gliclazide works by making your pancreas work harder to try to prouce more insulin. In LADA this can be counterproductive because your beta cells are dying - making your pancreas work harder is believed to speed up the progression into full Type 1. MODY, which is a genetic form of diabetes, is sometimes controlled very well by Gliclazide. Both LADA and MODY are referred to as Type 1.5, but they are very different forms of diabetes and should be treated differently. I have LADA and was put on Gliclazide for a short while before my proper diagnosis (they misdiagnosed me as Type 2), but the consultant took me off it very quickly once LADA was diagnosed. So I would advise you to question whether they really believe you are LADA and, if so, question the choice of Gliclazide. Google Gliclazide to get a better idea of how it works and why it might not be appropriate for LADA.</p><p></p><p>Good luck</p><p></p><p>Smidge</p></blockquote><p></p>
[QUOTE="smidge, post: 224027, member: 29301"] Hi Mishigato! Not sure if you've understood LADA properly? It is a form of Type 1 diabetes - it is a slow onset type and is sometimes called Type 1.5. It is generally diagnosed via a GAD antibody test. However, the problem is that while testing positive for GAD antibodies means you have the autoimmune form of diabetes, testing negative is inconclusive - it does not rule out LADA. Now, if you are being put in the LADA box, Gliclazide is probably not the best choice of drug. Gliclazide works by making your pancreas work harder to try to prouce more insulin. In LADA this can be counterproductive because your beta cells are dying - making your pancreas work harder is believed to speed up the progression into full Type 1. MODY, which is a genetic form of diabetes, is sometimes controlled very well by Gliclazide. Both LADA and MODY are referred to as Type 1.5, but they are very different forms of diabetes and should be treated differently. I have LADA and was put on Gliclazide for a short while before my proper diagnosis (they misdiagnosed me as Type 2), but the consultant took me off it very quickly once LADA was diagnosed. So I would advise you to question whether they really believe you are LADA and, if so, question the choice of Gliclazide. Google Gliclazide to get a better idea of how it works and why it might not be appropriate for LADA. Good luck Smidge [/QUOTE]
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