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Type 1.5/LADA Diabetes
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<blockquote data-quote="Chris24Main" data-source="post: 2723003" data-attributes="member: 585131"><p>It's a really tough question, and one that I think just doesn't have a simple answer - I was in a similar situation, though for me it was simply that my diagnosis was not clear for a while, and my notes from the time go into advice I was given about the likelihood that my pancreas was failing - or not. There was a lot of discussion about "reserves being used up" and "rates of destruction" - but essentially all my learning since would indicate that all the advice I was initially getting was wrong.</p><p></p><p>Not that this means I am correct, and one person's experience does not necessarily mean anything useful, but my experience was that all my doctors were of the opinion that the Pancreas would just get worse..</p><p></p><p>However, if you look at it all as a consequence of insulin resistance in the Pancreatic cells, then the treatment - pump in more insulin - will produce the observable result that the pancreas itself is failing, because your blood glucose will be increasing for a given dosage, so the conclusion will be to increase the dosage, and so it goes.</p><p></p><p>The flip of that (the other way of thinking about it) is that, by the time your blood glucose is showing very high, your pancreas is undoubtedly struggling to keep up with demand, so a period of exogenous insulin may be the thing that it needs to recover (provided you are doing something to reduce demand for insulin on an on-going basis, like reducing carbs).</p><p></p><p>But - the underlying question is really about the capacity of the pancreas to recover - or not. Most of what I've read and listened to gets into - there really isn't anything to suggest that a pancreas cannot recover. It's assumed, and statistically there are results that suggest... but there isn't anything definitive, and no mechanism that would explain a pancreas just losing it's ability (gradually over time rather than suddenly in childhood) to produce insulin.</p><p></p><p>Again - that's my reading of the literature, not an opinion that's worth anything in itself, but my takeaway is that as an individual, anything you can do to support the recovery of the pancreas should be attempted, and just accepting it as a lost cause feels wrong.</p></blockquote><p></p>
[QUOTE="Chris24Main, post: 2723003, member: 585131"] It's a really tough question, and one that I think just doesn't have a simple answer - I was in a similar situation, though for me it was simply that my diagnosis was not clear for a while, and my notes from the time go into advice I was given about the likelihood that my pancreas was failing - or not. There was a lot of discussion about "reserves being used up" and "rates of destruction" - but essentially all my learning since would indicate that all the advice I was initially getting was wrong. Not that this means I am correct, and one person's experience does not necessarily mean anything useful, but my experience was that all my doctors were of the opinion that the Pancreas would just get worse.. However, if you look at it all as a consequence of insulin resistance in the Pancreatic cells, then the treatment - pump in more insulin - will produce the observable result that the pancreas itself is failing, because your blood glucose will be increasing for a given dosage, so the conclusion will be to increase the dosage, and so it goes. The flip of that (the other way of thinking about it) is that, by the time your blood glucose is showing very high, your pancreas is undoubtedly struggling to keep up with demand, so a period of exogenous insulin may be the thing that it needs to recover (provided you are doing something to reduce demand for insulin on an on-going basis, like reducing carbs). But - the underlying question is really about the capacity of the pancreas to recover - or not. Most of what I've read and listened to gets into - there really isn't anything to suggest that a pancreas cannot recover. It's assumed, and statistically there are results that suggest... but there isn't anything definitive, and no mechanism that would explain a pancreas just losing it's ability (gradually over time rather than suddenly in childhood) to produce insulin. Again - that's my reading of the literature, not an opinion that's worth anything in itself, but my takeaway is that as an individual, anything you can do to support the recovery of the pancreas should be attempted, and just accepting it as a lost cause feels wrong. [/QUOTE]
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