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Another Nail In Statins' Coffin? We Can But Hope..
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<blockquote data-quote="SamJB" data-source="post: 1882364" data-attributes="member: 45322"><p>There's loads of statin-bashing on this forum, which I don't understand (genuinely, I'm not being antagonistic). Here's what I do understand (note, I've worked in clinical research for 6 years):</p><ul> <li data-xf-list-type="ul">Statins don't lower cholesterol. What is called "cholesterol" in context of lipid results, isn't cholesterol, it's lipoproteins.</li> <li data-xf-list-type="ul">Cholesterol is a simple fatty molecule, lipoproteins are complex proteins, one end is soluble in water, the other is soluble in fat. Lipoproteins can therefore form a ball and carry fat on the inside around the blood stream.</li> <li data-xf-list-type="ul">Statins are a very safe drug. Yes there are some adverse events reported, as there are with any drug, but on the whole are one of the safest drugs to use. I'm basing that on my clinical research where we I have monitored Adverse Events for a whole host of drugs across the clinical spectrum for 6 years.</li> </ul><p>What I don't understand is, what is the biomarker of blocked up arteries and do statins lower it? Do they reduce the plaques formed in the arteries?</p></blockquote><p></p>
[QUOTE="SamJB, post: 1882364, member: 45322"] There's loads of statin-bashing on this forum, which I don't understand (genuinely, I'm not being antagonistic). Here's what I do understand (note, I've worked in clinical research for 6 years): [LIST] [*]Statins don't lower cholesterol. What is called "cholesterol" in context of lipid results, isn't cholesterol, it's lipoproteins. [*]Cholesterol is a simple fatty molecule, lipoproteins are complex proteins, one end is soluble in water, the other is soluble in fat. Lipoproteins can therefore form a ball and carry fat on the inside around the blood stream. [*]Statins are a very safe drug. Yes there are some adverse events reported, as there are with any drug, but on the whole are one of the safest drugs to use. I'm basing that on my clinical research where we I have monitored Adverse Events for a whole host of drugs across the clinical spectrum for 6 years. [/LIST] What I don't understand is, what is the biomarker of blocked up arteries and do statins lower it? Do they reduce the plaques formed in the arteries? [/QUOTE]
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