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Another potential nail in LDL's coffin ?
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<blockquote data-quote="librarising" data-source="post: 1674840" data-attributes="member: 41957"><p>Dave Feldman, author of the Cholesterol Code website, has just published a new article</p><p><a href="http://cholesterolcode.com/remnant-cholesterol-what-every-low-carber-should-know/" target="_blank">http://cholesterolcode.com/remnant-cholesterol-what-every-low-carber-should-know/</a></p><p></p><p>I'd never even heard of remnant cholesterol, yet he concludes</p><p>"I’m hesitant to name any single lipid marker as the “best” one to measure. But if I had to choose right now, I’d be pointing to Remnant Cholesterol (RC). As of this writing, I haven’t found a single study that includes RCs in matchups with other lipids where it isn’t the clear winner in predicting all-cause mortality."</p><p></p><p>Remnant Cholesterol (RC) is simply TC - (HDL + LDL)</p><p></p><p>His article includes a link to a calculator. Over the last 7 years my RC has gone from 1.1 to 0.5 mmol/L, and from 21.5% to 9.6%. The relevance of these are shown here :</p><p><a href="http://cholesterolcode.com/wp-content/uploads/2018/01/remnant_vs_ldl-1.jpg" target="_blank">http://cholesterolcode.com/wp-content/uploads/2018/01/remnant_vs_ldl-1.jpg</a></p><p></p><p>I don't fully get what he's saying in the What This Means For Low Carbers section :</p><p>"the reference range for RCs as they apply to those on a fat-based diet may actually be inflated. In other words, I’d expect RCs to actually be higher for appropriate mechanistic reasons given the higher <em>proportion</em> of distribution by VLDLs when LCHF/Keto"</p><p></p><p>I'm only at the beginning of this RC learning curve, so this post is a heads-up to those interested.</p><p>Geoff</p></blockquote><p></p>
[QUOTE="librarising, post: 1674840, member: 41957"] Dave Feldman, author of the Cholesterol Code website, has just published a new article [URL]http://cholesterolcode.com/remnant-cholesterol-what-every-low-carber-should-know/[/URL] I'd never even heard of remnant cholesterol, yet he concludes "I’m hesitant to name any single lipid marker as the “best” one to measure. But if I had to choose right now, I’d be pointing to Remnant Cholesterol (RC). As of this writing, I haven’t found a single study that includes RCs in matchups with other lipids where it isn’t the clear winner in predicting all-cause mortality." Remnant Cholesterol (RC) is simply TC - (HDL + LDL) His article includes a link to a calculator. Over the last 7 years my RC has gone from 1.1 to 0.5 mmol/L, and from 21.5% to 9.6%. The relevance of these are shown here : [URL]http://cholesterolcode.com/wp-content/uploads/2018/01/remnant_vs_ldl-1.jpg[/URL] I don't fully get what he's saying in the What This Means For Low Carbers section : "the reference range for RCs as they apply to those on a fat-based diet may actually be inflated. In other words, I’d expect RCs to actually be higher for appropriate mechanistic reasons given the higher [I]proportion[/I] of distribution by VLDLs when LCHF/Keto" I'm only at the beginning of this RC learning curve, so this post is a heads-up to those interested. Geoff [/QUOTE]
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