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Message: <blockquote data-quote="Daibell" data-source="post: 1867927" data-attributes="member: 21149"><p>Hi. There is a  problem with the strict definition of T1 i.e. that it is an auto-immune condition and will therefore have anti-bodies showing up. There are other reasons why the beta cells can fail with no normal antibodies showing and rather stupidly these conditions are excluded and dumped in the T2 category. Viruses can cause beta cell failure and I suspect that is why I have very low insulin but no GAD antibodies showing. NICE also says that the GAD test can be negative a few years after T1 diagnosis. The c-peptide test can help show whether your insulin is low. In practice if you need insulin it really doesn't matter what the diagnosis is. Your BMI is a bit on the high side but unexpected weight loss is a pointer to beta cell failure so I suggest you can either try Gliclazide or similar for a while to stimulate the pancreas or ask the consultant to start insulin</p></blockquote><p></p>

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