After having kept my A1c under control for 18 month, the last one was up from 6.7 to 8.8 :shock: . Now I had already decided to plead with the doctor to change me from Metformin when I went to see him because I have never lost the awful stomach cramps and terrible diahorrea even on the SR version. My diet hasnt changed and I'm still being careful with carbs. Anyway I managed to see our "diabetic" doctor who changed my medication to a combination of Actos and Amaryl. Can anyone tell me how long i would expect to have to take these drugs to see any appreciable decline in my blood sugars. the only thing I have noticed is a slight lowering of morning levels but still not good, probably around 8.8. Oh and miracle of miracles, she gave me a prescription for test strips...what a love, I usually buy them
Hi Giblet
When I started the glimepiride (Amaryl) it took so long to kick in that I asked my friendly neighbourhood pharmacist how long it took to get up to speed and she suggested up to 10 days (I'd been taking it just over a week by then) and this turned out to be about right for me. Don't know what the literature says about this, but that was my experience.
Cheers, BB
PS it does work - I came off mine for a week recently as an experiment (not recommended but I was bored) and my BG levels went up from 4-6 average, to 6-8. I'm low-carbing and wasn't a happy bunny so I went back on them within the week and my levels came back down again almost immediately.