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<blockquote data-quote="Oldvatr" data-source="post: 1496552" data-attributes="member: 196898"><p>The 'certain areas' you refer to are external surface skin areas, but this is in an Oral med taken internally. The shellac resin is indeed a varnish coating, amd refers to the SR prolonged release enteric coating layer of the tab. again, not sure how healthy it is when taken orally. The propylene glycol ingredient is the main ingredient in the base if my hemorroid cream, and also in the base for the Canesten and clotrimazole ointments I have to use on my external areas occasionally. Again, this is an oral application, and the glycol is actually a plasticiser. None of these ingredients here is needed in a standard release variant of the Metformin tab, but is actually present in any film coated tab, which most modern meds are sold nowadays, so we are stuck with these ingredients anyway. The shellac seems to be only applicable to the SR variants, and may be the time delay enteric ingredient.</p><p></p><p>for standard film coated tab, it has</p><p>Film coating is: opadry white OY−L−28900 consisting of lactose monohydrate,</p><p>methylhydroxypropylcellulose, titanium dioxide (E171), polyethylene glycol 4000 and purified water.</p><p></p><p></p><p>I have asked my GP to put me back on standard release since I have experienced problems with the XR / SR versions of Glucophage before, and although it is probably a side effect of the ACE inhibitor and the PPI I am using, there may be others who may find similar reaction to an unannounced med swap for a so called generic med that is actually different from what we were using before the CCG bean counter stepped in.</p><p></p><p>My Gp has just rung me to change my scrip back to standard, and it seems I am not the only one reporting difficulty with the changed med this month.</p></blockquote><p></p>
[QUOTE="Oldvatr, post: 1496552, member: 196898"] The 'certain areas' you refer to are external surface skin areas, but this is in an Oral med taken internally. The shellac resin is indeed a varnish coating, amd refers to the SR prolonged release enteric coating layer of the tab. again, not sure how healthy it is when taken orally. The propylene glycol ingredient is the main ingredient in the base if my hemorroid cream, and also in the base for the Canesten and clotrimazole ointments I have to use on my external areas occasionally. Again, this is an oral application, and the glycol is actually a plasticiser. None of these ingredients here is needed in a standard release variant of the Metformin tab, but is actually present in any film coated tab, which most modern meds are sold nowadays, so we are stuck with these ingredients anyway. The shellac seems to be only applicable to the SR variants, and may be the time delay enteric ingredient. for standard film coated tab, it has Film coating is: opadry white OY−L−28900 consisting of lactose monohydrate, methylhydroxypropylcellulose, titanium dioxide (E171), polyethylene glycol 4000 and purified water. I have asked my GP to put me back on standard release since I have experienced problems with the XR / SR versions of Glucophage before, and although it is probably a side effect of the ACE inhibitor and the PPI I am using, there may be others who may find similar reaction to an unannounced med swap for a so called generic med that is actually different from what we were using before the CCG bean counter stepped in. My Gp has just rung me to change my scrip back to standard, and it seems I am not the only one reporting difficulty with the changed med this month. [/QUOTE]
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