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<blockquote data-quote="tim2000s" data-source="post: 1331873" data-attributes="member: 30007"><p>It rarely does. One of the biggest items that the ongoing artificial pancreas trials have identified is that the 1, 12, 24 or 48 block model is highly inexact and unrealistic. It's very rare for any two days to have the same basal requirements and although a basal profile provides a fall back in the event of something failing, you should really consider the multiple TBRs as 5 minute square wave boluses - effectively a microbolus model.</p><p></p><p>Because it is reacting to the changes in its predicted glucose level constantly, it's not really a basal profile that you are looking at, as it is also affected by food consumption.</p><p></p><p>The image below shows two days where I ate different foods and did mostly similar things, and the differences in the adjustment of basal insulin on both days. We all have a variety of factors that affect our insulin sensitivity and these also affect our insulin requirements. Think of it more like never needing a "Weekday" profile, a "weekend" profile and a "nights" profile as the system will always adjust appropriately.</p><p></p><p>[ATTACH=full]21364[/ATTACH]</p></blockquote><p></p>
[QUOTE="tim2000s, post: 1331873, member: 30007"] It rarely does. One of the biggest items that the ongoing artificial pancreas trials have identified is that the 1, 12, 24 or 48 block model is highly inexact and unrealistic. It's very rare for any two days to have the same basal requirements and although a basal profile provides a fall back in the event of something failing, you should really consider the multiple TBRs as 5 minute square wave boluses - effectively a microbolus model. Because it is reacting to the changes in its predicted glucose level constantly, it's not really a basal profile that you are looking at, as it is also affected by food consumption. The image below shows two days where I ate different foods and did mostly similar things, and the differences in the adjustment of basal insulin on both days. We all have a variety of factors that affect our insulin sensitivity and these also affect our insulin requirements. Think of it more like never needing a "Weekday" profile, a "weekend" profile and a "nights" profile as the system will always adjust appropriately. [ATTACH=full]21364[/ATTACH] [/QUOTE]
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